A 30,000-year-old genome from a woman buried in the Isturitz cave in the French Pyrenees has become the oldest complete human genome from southwestern Europe, revealing that Ice Age hunter-gatherer groups were genetically connected across vast distances. The findings, published in Science Advances by a team led by Pere Gelabert and Ron Pinhasi of the University of Vienna, challenge previous genetic evidence that suggested two major lineages — the Fournol cluster in the west and the Věstonice cluster in central and eastern Europe — remained isolated throughout the Gravettian period (34,000–25,000 years ago) .
The key to the discovery was a long bone excavated from Isturitz in the 1950s and stored at the Institute of Human Paleontology in Paris. A sample taken in 2013 was radiocarbon-dated to around 30,000 years ago. The genome, with over 450,000 genetic markers, showed the woman's ancestry was predominantly Fournol, but a smaller fraction matched the Věstonice lineage, whose closest known sites are about 1,500 kilometers away in the Czech Republic . Statistical modeling estimated this mixing occurred between 32,500 and 31,500 years ago, one or two millennia before the woman lived .
The study adds a new dimension to understanding Gravettian populations, showing that long-distance genetic exchange occurred despite the apparent stability of the two main lineages. Researchers note that the analysis assumes a single admixture event, which remains a hypothesis . The discovery also highlights the potential of re-examining museum collections for ancient DNA.