Thiago Tirante produced the biggest win of his career by eliminating Novak Djokovic in the second round of the Cincinnati Masters, then backed it up with a straight-sets victory over Martín Landaluce to reach the fourth round. The Argentine, ranked 50th, beat the 24-time Grand Slam champion 2-6, 6-4, 6-4 in 2 hours 44 minutes, ending Djokovic's 10-match winning streak at the tournament . Djokovic, who had not lost in Cincinnati since 2019, struggled physically in the heat and humidity, requiring medical attention early in the second set . After the match, Djokovic revealed he suffers from a chronic health condition aggravated by such conditions: "It's a health problem I've had for many years. It causes me a lot of problems, especially when it's very humid and hot" . He also cast doubt on returning to Cincinnati, saying "right now it seems more likely that I won't" . Tirante, who debuted in the Top 50 this week, then defeated Landaluce 7-6(5), 7-6(4) in 136 minutes, hitting nine aces . The win extended his run to a third consecutive Masters 1000 fourth-round appearance . Landaluce, 20, was later named to Spain's Davis Cup team for the qualifier against Chile in September, without the injured Carlos Alcaraz . Other notable results included Ben Shelton's early exit to Jaime Faria, and Juan Manuel Cerúndolo's marathon win over Arthur Rinderknech .
