A partnership between the Instituto Tecnológico de Santo Domingo (INTEC) and AI Robotix has produced an artificial intelligence platform designed to accelerate Alzheimer’s disease research. The system has already processed more than 232,000 scientific articles and genetic databases, isolating 3,223 datasets with potential to generate new hypotheses about the disease’s origin and progression Source: Hoy. Unlike conventional tools, the platform aims to create and test novel scientific hypotheses, discarding weak ones early to focus efforts on the most promising avenues for diagnosis, prevention, or treatment.
The platform integrates global supercomputing networks, including NVIDIA BioNeMo, Amazon BioDiscovery, and Cloud Sciences, to run molecular simulations Source: Hoy. As a first proof of concept, it completed computational simulations of brain mechanics related to Alzheimer’s.
To guide clinical validation, the project has brought on board Argentine neurologist Ricardo Francisco Allegri as principal investigator, whose experience in neurodegenerative diseases will help set scientific priorities and oversee methodology Source: Listín Diario. Juan Carlos Guilbe, CEO of AI Robotix and project founder, highlighted that Allegri’s role strengthens the link between AI-generated proposals and rigorous preclinical studies.
Manuel Colomer, an INTEC epidemiologist, stated that the team expects to produce scientific publications in the second half of this year and early next year to transform how Alzheimer’s is approached Source: Listín Diario. The project is also building international collaborations through Germán Cavelier, formerly of the U.S. National Institutes of Health.
“En lo que va de este año, la herramienta ha procesado más de 232,000 artículos científicos y bases de datos genéticas, incluyendo repositorios públicos y privados de secuenciación RNA-Seq.”
“Su objetivo es generar nuevas hipótesis científicas, contrastarlas con la evidencia disponible y descartar tempranamente aquellas que no presenten suficiente sustento.”
“Allegri describió el proyecto como 'desafiante' al considerar el Alzheimer es una enfermedad que aumenta con la edad y la población envejece lo que aumenta la prevalencia de la enfermedad.”
“Manuel Colomer ... indicó que desde el área de salud de INTEC apoyan la iniciativa y adelantó que el equipo espera producir publicaciones científicas durante la segunda mitad de este año y principios del próximo.”