A new study presented at the Alzheimer’s Association International Conference (AAIC) 2026 finds that retired professional soccer players experience higher rates of depression and anxiety alongside structural brain changes, though no measurable cognitive decline was detected Source: CNN. The research, led by Imperial College London, compared 142 former players aged 30–60 with 56 healthy non-players Source: Euronews.
Only 2% of former athletes exhibited signs of severe brain shrinkage indicative of active neurodegeneration Source: CNA. Researchers caution that the findings are preliminary and do not establish a direct link to Alzheimer’s or CTE Source: CNN. “We're at a very early stage of translating these findings to individual risk prediction,” said senior author Dr. Thomas Parker Source: CNA. The team plans to follow participants every two years to track long-term trajectories Source: Euronews.
“nearly a third of the 142 professional former players in the study had symptoms serious enough to be classed as clinical depression, compared with just 9% of the comparison group. For anxiety, 42% of players met the threshold, against 25% of non-players.”
“31 per cent meeting the threshold for clinical depression compared to 9 per cent of the control group, and 42 per cent reporting clinical anxiety compared to 25 per cent.”
“brain scans did show lower gray matter — the brain’s information processor — in regions that affect memory, decision-making, attention and emotional regulation among the group of players.”
“Only 2 per cent of the former athletes showed individual signs of severe brain shrinkage that would point to active, progressive neurodegeneration.”